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Fig. 1 | Genome Medicine

Fig. 1

From: PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data

Fig. 1

PanDrugs score calculation. a Overview of the DScore and GScore calculation and their corresponding annotation sources. PanDrugs considers drug indication and status, gene–drug associations and number of hits to calculate the DScore. GScore is estimated according to gene essentiality and tumoral vulnerability, gene relevance in cancer, the biological impact of mutations, the frequency of gene alterations, and their clinical implications. b PanDrugs considers the “Best therapeutic candidates” based on the accumulated and weighted scoring of GScore and DScore

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