Skip to main content
Fig. 1 | Genome Medicine

Fig. 1

From: Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers

Fig. 1

The DNA methylation landscape of hepatocellular carcinoma. a Seven methylation clusters were obtained from k-means consensus clustering. Rows are 591 CpGs that had high variation (SD > 0.2) in tumor tissues and low (β value < 0.05) methylation level in normal tissues. Cluster 7 (purple) showed a hypermethylation pattern in nearly all CpGs and was regarded as the CpG island methylator phenotype. b Kaplan-Meier survival curves of each cluster. The CIMP group had a poorer survival than other clusters. c Characteristics of the clusters. Significance was obtained from Fisher’s exact test (p value < 0.05). d Overall survival of CIMP and non-CIMP patients. e Overall survival of CIMP stage III and non-CIMP stage III patients

Back to article page