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Table 1 Comparison of the performance of different methylation markers for classifying HCC and normal tissues

From: Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers

Markers Two HCC-specific CpGs Six HCC-specific CpGs Nine CpGs of Zheng et al.a Seven CpGs of Xu et al.b
Sensitivity
 GSE54503 0.848 0.909 0.970 0.833
 GSE89852 0.892 0.919 0.919 0.946
 GSE56588 0.920 0.924 0.942 0.741
Specificity
 GSE54503 0.970 0.970 0.970 0.955
 GSE89852 0.973 0.973 0.892 0.919
 GSE56588 1.000 1.000 1.000 1.000
  1. aZheng et al. [16] reported ten CpGs as HCC diagnostic markers. Nine of them had methylation values in TCGA HCC dataset
  2. bXu et al. [17] reported ten CpGs as HCC diagnostic markers. Seven of them had methylation values in TCGA HCC dataset
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Genome Medicine

ISSN: 1756-994X

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