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Table 1 Demographics and disease status of cohorts from four brain bank resources

From: Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

 

Mayo

MSBB

DIAN

Knight-ADRC

Sample size

191

300

19

103

Age (years)

83 ± 7.77

83.3 ± 7.55

50.6 ± 7.06

85.1 ± 9.78

Male (%)

45.5

36

68.4

38.8

APOE ε4+ (%)

33.2

31.7

14.3

45.6

Brain weight

1187.7 ± 184.5

1138.1 ± 142.5

AD

82

135

19

87

PA

29

0

0

0

Control

80

85

0

16

CDR = 0

40

0

13

CDR = 0.5

40

0

9

CDR = 1

30

2

11

CDR = 2

44

4

14

CDR = 3

146

1

56

  1. Mayo Mayo Clinic, MSBB Mount Sinai Brain Bank, AD Alzheimer’s disease, PA pathological aging, CDR Clinical Dementia Rating for available samples