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Fig. 2 | Genome Medicine

Fig. 2

From: Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease

Fig. 2

MCH has a significant effect on the reasoning cognition in multiple MR analysis approaches. a Mendelian randomisation model used for analysis. b p values are significant (> 0.005) in multiple MR methods for the MCH measure (exposure) in the reasoning and numeric traits. Significance in more than one test method is important to rule out pleiotropy among instruments. c MCH instrument (SNP) causal estimates for the reasoning (outcome) show symmetry about 0 indicating a robust analysis (without pleiotropy). d MCH instrument causal estimates for the numeric trait. e Instrument causal estimates for the reasoning trait compared to RDW

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Genome Medicine

ISSN: 1756-994X

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