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Table 3 Significant Differences for red blood cell measures in an independent sample set

From: Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease

 

AD case–control

AD case–control

MMSE

 

T test

KS test

T test

KS test

Beta

p value

Red

 Red blood cell count (RBC)

2.65 × 10 −03

2.21 × 10 −04

4.06 × 10 −04

5.63 × 10 −04

0.02

7.04 × 10 −03

 Haemoglobin (HGB)

0.036

1.92 × 10 −03

4.06 × 10 −04

2.25 × 10 −04

0.04

0.036

 Packed cell volume (PCV)

9.42 × 10 −04

1.61 × 10 −06

4.06 × 10 −04

2.25 × 10 −04

0.002

0.026

 Mean corpuscular volume (MCV)

0.033

1.95 × 10 −03

0.483

0.092

0.01

0.929

 Mean corpuscular haemoglobin (MCH)

0.036

1.92 × 10 −03

0.244

0.054

− 0.05

0.027

 Red cell distribution width (RDW)

0.103

0.142

0.609

0.606

0.01

0.868

White

 Platelet (PLT)

0.036

1.55 × 10 −03

0.244

0.092

− 1.18

0.369

 Platelet distribution width (PDW)

0.036

0.142

0.244

0.606

− 0.36

0.369

 White blood cell (WBC)

0.382

0.345

0.944

0.609

0.05

0.929

 Neutrophils

0.729

0.105

0.992

0.487

− 0.02

0.914

 Lymphocytes

0.867

0.379

0.944

0.154

0.00

0.929

 Monocytes

0.867

0.379

0.944

0.606

0.00

0.914

 Eosinophils

0.867

0.030

0.944

0.361

0.00

0.369

 Basophils

0.382

0.105

0.449

0.065

0.00

0.127

  1. The AddNeuroMed dataset was divided by two variables for testing. Cases and control groups were compared by t test and Kolmogorov–Smirnov (KS) tests. MMSE was used to split samples into two groups for t and Kolmogorov–Smirnov (KS) tests. Results using MMSE from all samples using a linear model are also shown (beta estimate and p value given). Significant results are marked with italic fonts (p < 0.05)