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Table 1 The mRNA microarray gene expression and RNA-Seq data used in this study. The dataset title is used hereafter as a dataset identifier

From: Therapy-induced stress response is associated with downregulation of pre-mRNA splicing in cancer cells

Dataset Cancer type Time after treatment (h) Number of samples
Control After treatment
I. Platinum-based agents
 E-GEOD-38122 [103] Hepatocyte carcinoma 24 3 3
 GSE47980 [104] Melanoma 24 9 9
 GSE38545 Ovarian cancer 24 3 3
 GSE13525 [105] Ovarian cancer 24 2 2
 E-GEOD-8057 [106] Ovarian cancer 24 4 4
 GSE51952 [107] Hepatocyte carcinoma 24 3 3
 GSE66493 Glioblastoma 24 3 3
 GDS3910 [108] Breast cancer 11 2 2
 E-MTAB-3645 [109] Ovarian cancer 72 3 3
II. Paclitaxel
 E-GEOD-50831 [110] Ovarian cancer 24 63 63
 E-GEOD-50830 [110] Endometrial adenocarcinoma 24 55 57
 E-GEOD-50811 [110] Breast cancer 24 79 81
III. Irradiation (two meta-analyses for cancer and embryonic cells)
 E-GEOD-59732 [111] Breast cancer 24 48 48
 E-GEOD-59861 [112] Skin fibroblasts 0, 3, 6, 12, 24 4 12
IV. Hypoxia
 E-GEOD-18494 [113] Hepatocyte carcinoma, glioblastoma, breast cancer 12 9 9
 E-GEOD-53012 [114] Prostate cancer, ovarian cancer, melanoma 72 9 9
 E-MTAB-3645 [109] Ovarian cancer 72 3 3
 E-GEOD-17188 [115] Breast cancer 24 4 4
V. Tyrosine kinase inhibitors
 E-TABM-585 [116] Lung cancer 20 21 27
VI. Topoisomerase inhibitors
 E-GEOD-47013 [117] Multiple myeloma 3 3
 E-GEOD-13477 [118] Breast cancer 24 2 2
 E-GEOD-19638 [119] Breast cancer 2 2
 E-GEOD-39870 [120] Breast cancer 3 3
Splicing analysis
 GSE69405 [37] Lung adenocarcinoma 48 12 12
 GSE89127 [34] Gastric carcinoma, lung adenocarcinoma, melanoma, urinary bladder carcinoma 48 18 18
Spliceostatin
 GSE72156 [58] Cervical cancer 3 3
Pladienolide
 E-GEOD-67770 [57] Ovarian cancer 2 2