Skip to main content

Table 1 Homozygous single nucleotide polymorphisms (SNPs) in P. falciparum drug resistance gene orthologs detected in the 69 Plasmodium vivax sequences

From: Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing

Locus Chr Position Ref Alt Amino acid Samples*
pvcrt-0 (PVX_087980) 1 331,151 T C Intron 61 (67)
331,819 G A Intron 29 (69)
332,453 T C Intron 59 (68)
332,874 A C Intron 67 (68)
pvdhfr (PVX_089950) 5 964,760 C G Phe57Leu 2 (66)
964,762 G A Ser58Asn 4 (63)
964,763 C G,A Ser58Arg 55 (59)
964,939 G A Ser117Asn 58 (62)
pvmdr1 (PVX_080100) 10 362,888 A G Phe1070Leu 6 (49)
363,223 A G Thr958Met 44 (46)
363,374 T G Met908Leu 46 (47)
365,435 C A Val221Leu 9 (49)
Multidrug resistance protein 2 (PVX_118100) 12 2,413,549 A T Tyr514Phe 6 (58)
2,415,530 G T Gln1174His 23 (57)
2,415,666 G A Gly1220Ser 11 (60)
2,416,390 C T Ala1461Val 1 (63)
2,416,408 T C Val1467Ala 31 (41)
2,416,420 T C Leu1471Pro 12 (62)
2,416,438 T C Leu1477Pro 2 (63)
Multidrug resistance-associated protein 2 (PVX_124085) 14 2,043,859 G C Gln1407Glu 11 (13)
2,045,050 C T Val1010Met 14 (15)
2,047,090 G A Pro330Ser 1 (15)
2,047,233 C A Arg282Met 13 (14)
2,047,816 C G Glu88Gln 3 (18)
dhps (PVX_123230) 14 1,257,856 G C Ala383Gly 9 (15)
1,258,389 C T Met205Ile 10 (12)
  1. *Samples column indicates the number of samples with the alternate allele, with the total number of samples genotyped in parentheses