Fig. 5

Effects of teriflunomide on infection with trVLPs. Cells were infected with either EBOV or JUNV trVLPs containing their respective minigenomes, and incubated for 48 h in the presence of the indicated amounts of teriflunomide. Afterwards, minigenome-encoded reporter activity was measured in the infected cells and is graphed on a logarithmic scale relative to untreated controls. Means and standard deviations of 12 biological replicates from 3 independent experiments are shown