TY - JOUR AU - Giulieri, Stefano G. AU - Baines, Sarah L. AU - Guerillot, Romain AU - Seemann, Torsten AU - Gonçalves da Silva, Anders AU - Schultz, Mark AU - Massey, Ruth C. AU - Holmes, Natasha E. AU - Stinear, Timothy P. AU - Howden, Benjamin P. PY - 2018 DA - 2018/08/23 TI - Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia JO - Genome Medicine SP - 65 VL - 10 IS - 1 AB - Large-scale genomic studies of within-host diversity in Staphylococcus aureus bacteraemia (SAB) are needed to understanding bacterial adaptation underlying persistence and thus refining the role of genomics in management of SAB. However, available comparative genomic studies of sequential SAB isolates have tended to focus on selected cases of unusually prolonged bacteraemia, where secondary antimicrobial resistance has developed. SN - 1756-994X UR - https://doi.org/10.1186/s13073-018-0574-x DO - 10.1186/s13073-018-0574-x ID - Giulieri2018 ER -