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Table 3 Top 20 differentially variable positions between RA-affected and non-RA twins. Probe names are shown, along with t-statistic p value, Bartlett’s test for differential variability, which group was hypervariable, and probe annotation

From: Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins

Probe P(tt) P(BT) Hypervariable group Chr Relationship to gene Gene symbol
cg11374732 0.000513329 4.09E−06 RA 2 Body INPP5D
cg01999539 0.000614047 1.50E−05 RA 6   
cg23280983 0.000689806 2.11E−05 RA 2 TSS200 C2orf42
cg20500144 0.000950244 6.82E−05 RA 3 Body ARL6IP5
cg26985354 0.001008386 2.18E−08 RA 19 Body SFRS16
cg26827503 0.001032395 2.68E−05 RA 4 Body TMEM156
cg11913894 0.001053694 2.93E−06 RA 6 TSS1500 MAP3K4
cg16583193 0.001125272 4.49E−06 RA 19 Body PIP5K1C
cg15573998 0.001139278 3.52E−05 RA 2 Body NRXN1
cg16012388 0.001186516 5.35E−06 RA 10 Body BICC1
cg16397722 0.00119032 9.50E−06 RA 17 Body TP53
cg20556304 0.001192582 3.94E−11 RA 6   
cg25173129 0.00134302 2.51E−07 Healthy 17 TSS1500 EPX
cg01928104 0.001384944 3.10E−06 RA 14 TSS1500 SNORD114-7
cg06734169 0.001534366 4.20E−07 RA 3 5′UTR LRRFIP2
cg04845047 0.00156418 4.88E−05 RA 13   
cg26788916 0.001792861 7.32E−05 RA 20   
cg00340024 0.001861004 3.01E−05 RA 1   
cg08306614 0.001980509 1.42E−05 RA 7 3′UTR NUDCD3
cg19929189 0.001981039 3.59E−09 RA 6   
  1. P(tt) t-statistic p value, P(BT) Bartlett’s test p value, Chr chromosome