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Table 1 SNP-based maternal and fetal heritability for maternal and neonatal chemokines and cytokines

From: Cross-genetic determination of maternal and neonatal immune mediators during pregnancy

SIM

Dataset

Maternal genetics

Fetal genetics

h 2 g

SE

P value

h 2 g

SE

P value

Chemokines

 CXCL10

Mothers

0.79

0.28

4.4 × 10−3

0.99

0.38

5.8 × 10−4

 CCL1

Infants

0.72

0.35

2.9 × 10−2

0.98

0.35

1.6 × 10− 2

 CCL3

Infants

0.60

0.33

4.6 × 10−2

0.72

0.43

5.0 × 10−2

 CCL17

Infants

0.59

0.37

0.09

0.99

0.42

1.0 × 10−2

 CCL19

Infants

0.69

0.36

4.0 × 10−2

0.99

0.42

7.8 × 10−3

 CCL22

Infants

0.92

0.32

3.8 × 10−3

0.97

0.43

2.0 × 10−2

 CCL25

Infants

0.50

0.33

0.07

0.70

0.42

5.0 × 10−2

 CXCL5

Infants

0.88

0.34

1.4 × 10−2

0.92

0.43

2.0 × 10−2

Cytokines

 IL-4

Infants

0.76

0.37

3.2 × 10−2

0.05

0.49

NS

 IL-7

Mothers

0.84

0.28

2.1 × 10−3

0.90

0.37

1.0 × 10−2

  1. NS not significant