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Fig. 2 | Genome Medicine

Fig. 2

From: Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation

Fig. 2

T helper cells upregulate IRE1a-XBP1 pathway in vivo during infection. Splenocytes from nematode (Nippostrongylus brasiliensis)-infected mouse (7 days post-infection) were stained with a PE-conjugated anti-XBP1s antibody and analyzed by flow cytometry (gating strategy: singlet > live cells > CD4+CD3e+ > XBP1s+). One representative FACS profile is displayed (left panel), and the graph containing all results (n = 4) is shown in the “right panel”

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