Fig. 4

Homologous recombination deficiency in exceptional short- and long-term HGSOC survivors. a Comparison of estimated tumor cell cellularity in the sequenced tumor tissue between long- (n = 20) and short- (n = 19) term HGSOC in this study. b Comparison of whole exome sequencing data derived HRD-LOH scores from tumors with greater than 50% tumor cellularity between exceptional survivor groups (long-term = 14, short-term 13). Individual data points in each group is shown in increasing order. Data points are colored by group, short-term in orange and long-term in purple. Boxplot for each group shows the group summary statistics for each survival group. Statistical significance is tested by non-parametric 2-sided Wilcoxon rank test for non-paired data and raw p values are reported. n.s. p > 0.05