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Table 5 Cross-validation performance for combined NNAlign models trained on single-allele data sets, with and without context information

From: Footprints of antigen processing boost MHC class II natural ligand predictions

 

Without context

With context

 

Allele

AUC 0.1

PPV

AUC 0.1

PPV

P value

DRB1*01:01

0.874

0.824

0.893

0.839

< 0.0001

DRB1*15:01

0.931

0.875

0.947

0.892

< 0.0001

DRB5*01:01

0.805

0.76

0.818

0.782

0.0368

  1. “Allele” refers to the combination of all data sets for that given allele used to train the model. Cross-validated performance values are reported as AUC 0.1 and PPV. P values were estimated using bootstrapping. For more details on these measures, refer to the “Methods” section
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Genome Medicine

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