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Fig. 1 | Genome Medicine

Fig. 1

From: Prevalence of pathogenic/likely pathogenic variants in the 24 cancer genes of the ACMG Secondary Findings v2.0 list in a large cancer cohort and ethnicity-matched controls

Fig. 1

Time required to review variants. Box-and-whisker plot of reviewer-reported per-variant time (in minutes) to conduct manual review of published literature and render a judgment on pathogenicity, as per ACMG/AMP guidelines. There were statistically significant differences in time to review all variants (blue; n = 115) vs. the first variant (red; n = 24) and first variant vs. subsequent variants (green; n = 91)

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