Skip to main content

Table 2 Demographic characteristics of controls

From: Prevalence of pathogenic/likely pathogenic variants in the 24 cancer genes of the ACMG Secondary Findings v2.0 list in a large cancer cohort and ethnicity-matched controls

Variable

CPSII

PLCO

EAGLE

Ancestry

European (CEU > 0.80)

Sex

M: 106 (49%)

F: 111 (51%)

M: 217 (59%)

F: 153 (41%)

M: 314 (79%)

F: 81 (21%)

Number of families

No families

Number of individuals

217

370

395

Average age (years)

71

67

66

Average follow-up (years)

11.1

9.3

N/A

Number of individuals with a cancer found during follow-up

7

32

Were not followed

  1. CEU Northern and Western European ancestry, CPSII Cancer Prevention Study II (American Cancer Society), EAGLE Environment and Genes in Lung Cancer Etiology, F female, M male, N/A not applicable, PLCO Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial