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Fig. 3 | Genome Medicine

Fig. 3

From: Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

Fig. 3

Multiple-trait colocalization analyses between cardiovascular traits and molecular phenotypes. a Evidence of colocalization between TMEM258 expression and total cholesterol (left) as well as DNA methylation at cg19610905 and total cholesterol (right) using data derived from whole blood. b Evidence of colocalization between SORT1 expression using data derived from the liver and total cholesterol (left). However, this evidence diminished when undertaking the same analysis for SORT1 expression data derived from whole blood (right). Abbreviations: TC, total cholesterol; eQTL, expression quantitative trait loci; mQTL, methylation quantitative trait loci

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