Table 1 Glossary of relevant abbreviations used

Var

Somatic variant (single nucleotide variant [SNV], insertion/deletion [InDel], frameshift variant)

Var^ns

Non-synonymous somatic variant (i.e., somatic mutation)

Var^exp

Expressed non-synonymous somatic variant

PNE

Predicted mutated neoepitope

PNE^exp

Predicted mutated neoepitope with evidence on transcript level

PNE^prot

Predicted mutated neoepitope with evidence on proteome level

NE^lig

Mutated neoantigen with evidence on HLA ligandome level (HLA class I)

WT^lig

Wild-type peptide corresponding to PNE with evidence on HLA ligandome level (HLA class I)

neoantigen/neoepitope

Mutated HLA-presented peptide (potentially) recognizable by (T cells of) the immune system

TMB

Tumor mutational burden (non-synonymous somatic variants per megabase)