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Fig. 8 | Genome Medicine

Fig. 8

From: A modular transcriptome map of mature B cell lymphomas

Fig. 8

Prognostic map and overall survival (OS) curves for selected groups of tumors. The prognostic map obtained reveals regions of worse prognosis in red and of better prognosis in blue (panel a). The dark blue region near spots K (HR < 0.5) and the maroon region near spot H (HR > 2) associate with best and worst prognosis, respectively. The respective OS curves (b) resemble that of the balanced proliferative HT and of ABC-DLBCL on the one side and that of the balanced inflammatory HT and of GCB-DLBCL on the other side (panels c and d). eh OS curves of the major subtypes (e) which are further stratified for children and adults for BL (f). OS curves of selected PATs (g) and of DLBCL-related PATs (h) associate spot combinations with prognosis. Hazard ratios (HR) are given for significantly differential curves with p value < 0.01 in Cox model. HRs which are still significant after adjustment for therapy are marked with an asterisk. See also Table S4 and Table S5 for HRs and p values of all pairwise comparisons and of the co-factors

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