Fig. 5

Leukemia/lymphoma oncoprint of most common Tier 1 and 2 SNVs, indels, and fusions. Summary of most commonly encountered Tier 1 or 2 SNVs and fusion variants identified in > 1 leukemia/lymphoma tumor. NRAS and KRAS hotspot variants were most common, followed by ETV6-RUNX1 fusions. Compared to solid tumors and CNS tumors, Leukemia and lymphomas were more likely to have multiple variants per tumor, represented across the top. The number of variants identified per gene is represented to the right. Age and tumor type are represented across the bottom. CNS = central nervous system, SNV = single nucleotide variant, indel = insertion/deletion