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Fig. 3 | Genome Medicine

Fig. 3

From: Prognostic value of B cells in cutaneous melanoma

Fig. 3

Unsupervised clustering of the TCGA SKCM samples according to BCR/TCR measurements. All TCGA melanoma samples (n = 473); samples with missing values were imputed for visualization purposes. For all BCR measurements missing values were replaced with a zero. Exceptions included evenness, which was replaced by one, and mean V-region identity, which was replaced by the median. Measurements were scaled and median-centered. Each row shows a BCR or TCR measurement, chain type represented by a different color in the row color bar. The columns correspond to samples. The column color bars represents the cluster assignment, the subtypes (TCGA RNA-seq, BAGS, B regulatory cell), and presence or absence of assembled chains

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