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Table 1 Univariate model: association of overall survival and each IGHG BCR measurement using Cox proportional hazard regression model. Multivariate model: association of overall survival and each IGHG BCR measurement after conditioning on clinical variables (tumor tissue site, sex, age at pathological diagnosis, and patient stage) using the log likelihood ratio test to determine p values and Cox proportional hazard regression model to determine the hazard ratio

From: Prognostic value of B cells in cutaneous melanoma

  Univariable Multivariable
Hazard ratio p value Hazard ratio p value
Species evenness 1.38 0.0017 1.45 0.0014
Total BCR counts 0.72 0.0102 0.72 0.0104
Shannon entropy 0.85 0.0464 0.88 0.1727
Species richness 0.82 0.0512 0.83 0.0864
1-Gini-Simpson 0.87 0.0856 0.92 0.3852
Top clone prop 1.13 0.1407 1.07 0.4970
Mean V-region identity 0.94 0.4604 1.01 0.9256
Total mutation load 0.87 0.5624 0.75 0.3381
Neo-antigen 1.01 0.8997 1.00 0.9736