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Table 1 Univariate model: association of overall survival and each IGHG BCR measurement using Cox proportional hazard regression model. Multivariate model: association of overall survival and each IGHG BCR measurement after conditioning on clinical variables (tumor tissue site, sex, age at pathological diagnosis, and patient stage) using the log likelihood ratio test to determine p values and Cox proportional hazard regression model to determine the hazard ratio

From: Prognostic value of B cells in cutaneous melanoma

 

Univariable

Multivariable

Hazard ratio

p value

Hazard ratio

p value

Species evenness

1.38

0.0017

1.45

0.0014

Total BCR counts

0.72

0.0102

0.72

0.0104

Shannon entropy

0.85

0.0464

0.88

0.1727

Species richness

0.82

0.0512

0.83

0.0864

1-Gini-Simpson

0.87

0.0856

0.92

0.3852

Top clone prop

1.13

0.1407

1.07

0.4970

Mean V-region identity

0.94

0.4604

1.01

0.9256

Total mutation load

0.87

0.5624

0.75

0.3381

Neo-antigen

1.01

0.8997

1.00

0.9736