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Table 2 Accuracy of the TBProfiler library

From: Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs

Drug Total Susceptible Resistant TB Profiler sensitivity (%) TB Profiler specificity (%)
Rifampicin 17,040 12,473 4564 95.9 98.2
Isoniazid 16,955 11,599 5295 93.7 98.1
Ethambutol 15,334 12,698 2617 92.1 91.7
Pyrazinamide 12,381 10,447 1875 87.6 96.7
Streptomycin 5366 3992 1288 78.0 96.3
Ethionamide 987 649 332 89.5 67.4
Amikacin 1480 1138 342 86.0 98.3
Capreomycin 1783 1388 393 84.7 95.9
Kanamycin 1908 1252 653 92.0 96.8
Ciprofloxacin 406 342 64 90.6 98.0
Moxifloxacin 905 798 107 86.0 91.9
Ofloxacin 2060 1543 514 90.1 96.5
Fluoroquinolones 2532 1944 539 89.1 97.1
PAS 418 373 42 23.8 96.7
Cycloserine 402 295 107 43.0 92.5
MDR-TB 16,879 11,293 4151 94.1 98.3
XDR-TB 2026 1681 343 83.4 96.4
  1. MDR-TB multi-drug-resistant TB, XDR-TB extensively drug-resistant TB, PAS para-aminosalicylic acid, − could not be determined