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Table 2 Accuracy of the TBProfiler library

From: Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs

Drug

Total

Susceptible

Resistant

TB Profiler sensitivity (%)

TB Profiler specificity (%)

Rifampicin

17,040

12,473

4564

95.9

98.2

Isoniazid

16,955

11,599

5295

93.7

98.1

Ethambutol

15,334

12,698

2617

92.1

91.7

Pyrazinamide

12,381

10,447

1875

87.6

96.7

Streptomycin

5366

3992

1288

78.0

96.3

Ethionamide

987

649

332

89.5

67.4

Amikacin

1480

1138

342

86.0

98.3

Capreomycin

1783

1388

393

84.7

95.9

Kanamycin

1908

1252

653

92.0

96.8

Ciprofloxacin

406

342

64

90.6

98.0

Moxifloxacin

905

798

107

86.0

91.9

Ofloxacin

2060

1543

514

90.1

96.5

Fluoroquinolones

2532

1944

539

89.1

97.1

PAS

418

373

42

23.8

96.7

Cycloserine

402

295

107

43.0

92.5

MDR-TB

16,879

11,293

4151

94.1

98.3

XDR-TB

2026

1681

343

83.4

96.4

  1. MDR-TB multi-drug-resistant TB, XDR-TB extensively drug-resistant TB, PAS para-aminosalicylic acid, − could not be determined