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Fig. 2 | Genome Medicine

Fig. 2

From: Evolving neoantigen profiles in colorectal cancers with DNA repair defects

Fig. 2

In vitro evolution of mutational landscape in 45 CRC cell lines. Mutational characterization of CRC cells after 90 days of culture (T90) in vitro. a Bar charts show the number of novel alterations (SNVs and frameshifts) acquired at T90 (not present at T0) for each cell line. b The number of predicted neoantigens (see the “Methods” section) is shown. Each bar represents putative neoepitopes derived from SNVs and frameshifts

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