Fig. 2
From: Evolving neoantigen profiles in colorectal cancers with DNA repair defects
In vitro evolution of mutational landscape in 45 CRC cell lines. Mutational characterization of CRC cells after 90 days of culture (T90) in vitro. a Bar charts show the number of novel alterations (SNVs and frameshifts) acquired at T90 (not present at T0) for each cell line. b The number of predicted neoantigens (see the “Methods” section) is shown. Each bar represents putative neoepitopes derived from SNVs and frameshifts