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Fig. 3 | Genome Medicine

Fig. 3

From: Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines

Fig. 3

Characterization of circRNAs generated from clinically actionable genes. a circRNA expression pattern in clinically actionable genes across cancer lineages. Red bars on the right panel represent the total number of cancer cell lines that identified each circRNA. b Permutation test of enrichment of circRNAs compared with randomly selected background gene list. Randomly selected background genes were sampled from genes with similar length, intron length, number of exons, or gene expression level. Vertical red lines indicate the percentage of clinically actionable genes that generated circRNAs. c Permutation test of number of RBP binding peaks on clinically actionable genes with randomly selected background gene list. Randomly selected background genes were sampled from genes with similar length, number of exons, or exon length. Vertical red lines indicate the median number of RBP binding peaks of clinically actionable genes

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