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Table 3 Comparison of classification results between VIC and CGI on four example datasets

From: Variant Interpretation for Cancer (VIC): a computational tool for assessing clinical impacts of somatic variants

VIC

CGI

Total

Known

Not protein-affecting

Predicted driver (Tier1/2)

Predicted passenger

Strong clinical significance

2

0

0

0

2 (0.42%)

Potential clinical significance

6

0

1

0

7 (1.48%)

Benign/likely benign

0

0

0

0

0 (0.00%)

Uncertain significance

0

110

8

347

465 (98.1%)

Total

8

110

9

347

474