Table 5 Comparison of classification results between VIC and OncoKB on two case series
VIC | Melanoma in OncoKB | Total | ||||
Oncogenic | Likely oncogenic | Predicted oncogenic | Likely neutral | Unknown/NA | ||
Strong clinical significance | 1 | 0 | 0 | 0 | 0 | 1 (0.35%) |
Potential clinical significance | 5 | 3 | 0 | 0 | 4 | 12 (4.26%) |
Benign/likely benign | 0 | 0 | 0 | 0 | 0 | 0 (0.00%) |
Uncertain significance | 3 | 30 | 5 | 1 | 233 | 272 (95.44%) |
Total | 9 | 33 | 5 | 1 | 237 | 285 |
VIC | NSCLC in OncoKB | Total | ||||
Oncogenic | Likely oncogenic | Predicted oncogenic | Likely neutral | Unknown/NA | ||
Strong clinical significance | 2 | 0 | 0 | 0 | 0 | 2 (0.82%) |
Potential clinical significance | 15 | 20 | 1 | 1 | 1 | 38 (15.57%) |
Benign/likely benign | 0 | 0 | 0 | 0 | 0 | 0 (0.00%) |
Uncertain significance | 5 | 39 | 7 | 1 | 152 | 204 (83.61%) |
Total | 22 | 59 | 8 | 2 | 153 | 244 |