Table 6 Comparison of classification results between VIC and CIViC on 645 variants from CIViC
VIC | CIViC* | Total | ||||
|---|---|---|---|---|---|---|
A | B | C | D | E | ||
Strong clinical significance | 0 | 4 | 5 | 4 | 0 | 13 (2.02%) |
Potential clinical significance | 1 | 33 | 174 | 81 | 2 | 291 (45.12%) |
Benign/likely benign | 0 | 4 | 0 | 0 | 0 | 4 (0.62%) |
Uncertain significance | 3 | 51 | 171 | 67 | 45 | 337 (52.25%) |
Total | 4 | 92 | 350 | 152 | 47 | 645 |