Fig. 4
From: Identifying chemogenetic interactions from CRISPR screens with drugZ
Tumor suppressor genes are frequent drug suppressor hits. a normZ plot hTERT-RPE1 screen for modifiers of gemcitabine activity, colored as in Fig. 3. b Gene essentiality of untreated hTERT-RPE1 cells. Purple, essential genes. Green, genes whose knockout imparts a fitness advantage. c normZ plot of A375 melanoma cell line screen for vemurafenib modifiers; data from [5]. d Gene essentiality scores for A375; data from [48]