Fig. 1From: Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertensionContribution of known PAH risk genes in the PAH Biobank cohort (n = 2572 cases). BMPR2, ACVRL1/ENG, TBX4. Other established risk genes included in the analysis: BMPR1A, BMPR1B, CAV1, EIF2AK4, KCNK3, SMAD4, and SMAD9. Newly validated risk genes: ABCC8, ATP13A1, GDF2, KCN5A, KLF2, SMAD1, and SOX17Back to article page