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Fig. 3 | Genome Medicine

Fig. 3

From: Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension

Fig. 3

Gene-based association analysis using 1832 European cases from all PAH subclasses and 12,771 European controls. a Results of a binomial test confined to rare LGD and D-Mis (REVEL variable threshold) variants in 20,000 protein-coding genes. Horizontal gray line indicates the Bonferroni-corrected threshold for significance. b Complete list of top association genes (p ≤ 0.001)

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Genome Medicine

ISSN: 1756-994X

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