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Table 1 Age, sex, and age-by-sex associations common to discovery and replication cohorts using both linear regression and MOMENT methods. The results shown correspond to the MOMENT output

From: An epigenome-wide association study of sex-specific chronological ageing

ProbeChrBPGeneOrientationDiscovery bDiscovery seDiscovery pReplication bReplication seReplication pPhenotype
cg080974177130,419,133KLF144.260.405E−272.450.237E−27Age
cg16867657611,044,877ELOVL2+5.050.404E−364.850.274E−71Age
cg105012101207,997,020NA+− 1.900.193E−23− 1.200.124E−23Age
cg075537613160,167,977TRIM59+1.910.334E−091.250.201E−10Age
cg236067182131,513,927FAM123C+2.450.321E−141.830.231E−15Age
cg028725462109,741,578NA− 3.630.516E−13− 1.940.332E−09Age
cg20351734X73,571,783NA− 6.900.634E−28− 5.810.444E−39Age
cg15833111X49,166,019GAGE10+− 3.600.463E−15− 2.410.263E−21Age
cg25140188X31,087,348NA+− 1.810.296E−10− 1.490.219E−13Age
cg13466600X77,587,444NA+− 6.100.718E−18− 3.630.465E−15Age
cg05517106X135,286,461FHL1+− 2.970.491E−09− 2.430.362E−11Age
cg11643285316,411,667RFTN1+− 0.090.012E−19− 0.160.015E−122Sex
cg095169631268,042,445DYRK2− 0.060.018E−22− 0.073.91E-32E−75Sex
cg051006341845,457,604SMAD2− 0.060.012E−30− 0.034.46E-32E−11Sex
cg103349162241,508,098RNPEPL1+0.030.012E−080.023.92E-32E−09Sex
cg165329382164,584,635FIGN− 0.120.021E−09− 0.150.013E−22Age-by-sex
cg06072257111,434,636NA+− 0.270.041E−11− 0.330.043E−18Age-by-sex
cg005318064190,938,709NA− 0.120.024E−11− 0.140.023E−16Age-by-sex
cg15833111X49,166,019GAGE10+0.220.021E−230.140.016E−27Age-by-sex
cg05548968X30,928,416NA0.140.024E−140.080.015E−09Age-by-sex
cg15475625X9,042,463NA0.210.031E−120.180.023E−14Age-by-sex
cg20202246X118,407,296NA0.210.037E−130.230.031E−15Age-by-sex
cg08814148X118,407,645NA+0.120.025E−100.130.018E−18Age-by-sex
cg24541420X135,691,028NA− 0.160.021E−15− 0.120.014E−16Age-by-sex