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Fig. 5 | Genome Medicine

Fig. 5

From: FIREVAT: finding reliable variants without artifacts in human cancer samples using etiologically relevant mutational signatures

Fig. 5

Currently known artifact signatures identified by FIREVAT in publicly available VCF callsets. There are four distinct types of artifacts that are currently identified by FIREVAT: (1) 8-oxo-guanine artifact, (2) FFPE-specific artifacts, (3) germline contamination, and (4) Thymine to Guanine (T>G) transversion artifact. The left column shows the 96 single nucleotide substitution peaks corresponding to each type of artifact. The middle column shows the quality metrics associated with each type of artifact and the last column lists the COSMIC mutational signatures (version 3) similar to the peaks observed in each artifact

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Genome Medicine

ISSN: 1756-994X

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