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Table 4 Novel virulence plasmids sequenced in this study and their host isolate properties

From: Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

IsolateVirulence plasmid (accession)iuc lineageAMR genesAMR genes elsewhere in genome
Sample data and chromosomal typing
Size and rep type(s)
2579
Nepal, 2016
ST15, KL112, ICEKp12
p2579_1
(MK649822)
182,805 bp
IncHI1B
iuc1qnrB1, strA^B, mphA, arr2, sulII^, dfrA14, blaOXA-232, blaCTX-M-15, blaTEM-30^
BA6740
India, 2016
ST11, KL24, ICEKp12
pBA6740_1 (MK649823)
226,590 bp
IncFIB(pQIL), IncFIIK
Iuc1qnrB1strA^B, rmtF, mphA, arr2, sulII, blaOXA-232, blaCTX-M-15, blaSHV-11, blaTEM-30^
BA813
India, 2017
ST2096, KL64, ICEKp5
pBA813_1
(MK649825)
273,676 bp
IncFIB(Mar), IncFIB
iuc1blaCTX-M-15, blaOXA-232, blaTEM-54^, aadA2^, armA, msrE, mphE^, catA1^, sulI, tetD, dfrA12, dfrA14Sat-2A, sulI, dfrA1, blaOXA-1
BA6201
India, 2017
ST231, KL51, ICEKp5
pBA6201_1 (MK649824)
195,016 bp
IncFIA, IncFIB(pQIL), IncFIIK, IncFII
iuc 1rmtF, mphA, ermB^, catA1^, arr2blaCTX-M-15, blaTEM-30^
16114547
Laos, 2016
ST290, KL21
p16114547_1 (MK649829)
187,989 bp
IncFIBK, IncFII
iuc 3qnrS1, tetA^, blaTEM-30^blaSHV-26^
1675474
Laos, 2015
ST7-1LV, KL54
p1675474_1 (MK649827)
181,647 bp
IncFIBK, IncFII
iuc 3catA2^, sulIIqnrS1, tetA^,
blaTEM-30^
1675479
Laos, 2015
ST945-2LV, KL125
p1675479_1 (MK649828)
167,992 bp
IncFIBK, IncFII
iuc 3strA^B, sulIItetA
130411–38618
Vietnam, 2011
ST17, KL127
p130411-38,618_1 (MK649826)
241,799 bp
IncFIBK, IncFIIK
iuc3strA^B, aadA1, cmlA5, floR, arr2^, sulII, tetA, dfrA14, blaOXA-10 
  1. *rep types as per the PlasmidFinder v2.0 database are shown. All plasmids carried the iuc aerobactin synthesis operon. No plasmids carried the iro or rmpA/rmpA2 virulence loci. Seven virulence plasmids also carried AMR (antimicrobial resistance) genes. Seven host isolates harboured additional AMR genes elsewhere in the genome. ST chromosomal multi-locus sequence type, KL K-locus. ^Inexact match