Skip to main content

Table 4 Association between relapse and genomic sequencing (N = 71)

From: Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

 Relapse or not 
CharacteristicsAll (N = 71)No relapse (N = 30)Relapse (N = 41)Fisher’s exact test
p value
UV
 Negative47 (66%)20 (67%)27 (66%)> 0.99
 Positive24 (34%)10 (33%)14 (34%) 
pRB status
 Mutate32 (45%)13 (43%)19 (46%)0.81
 Wild type39 (55%)17 (57%)22 (54%) 
p53 status
 Mutate31 (44%)13 (43%)18 (44%)> 0.99
 Wild type40 (56%)17 (57%)23 (56%) 
Virus positive or negative
 VN25 (35%)10 (33%)15 (37%)0.81
 VP46 (65%)20 (67%)26 (63%) 
pRB and p53
 pRB = M, p53 = M24 (34%)10 (33%)14 (34%)> 0.99
 pRB = M, p53 = W8 (11%)3 (10%)5 (12%) 
 pRB=W, p53 = M7 (10%)3 (10%)4 (10%) 
 pRB=W, p53 = W32 (45%)14 (47%)18 (44%)