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Table 4 Association between relapse and genomic sequencing (N = 71)

From: Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

 

Relapse or not

 

Characteristics

All (N = 71)

No relapse (N = 30)

Relapse (N = 41)

Fisher’s exact test

p value

UV

 Negative

47 (66%)

20 (67%)

27 (66%)

> 0.99

 Positive

24 (34%)

10 (33%)

14 (34%)

 

pRB status

 Mutate

32 (45%)

13 (43%)

19 (46%)

0.81

 Wild type

39 (55%)

17 (57%)

22 (54%)

 

p53 status

 Mutate

31 (44%)

13 (43%)

18 (44%)

> 0.99

 Wild type

40 (56%)

17 (57%)

23 (56%)

 

Virus positive or negative

 VN

25 (35%)

10 (33%)

15 (37%)

0.81

 VP

46 (65%)

20 (67%)

26 (63%)

 

pRB and p53

 pRB = M, p53 = M

24 (34%)

10 (33%)

14 (34%)

> 0.99

 pRB = M, p53 = W

8 (11%)

3 (10%)

5 (12%)

 

 pRB=W, p53 = M

7 (10%)

3 (10%)

4 (10%)

 

 pRB=W, p53 = W

32 (45%)

14 (47%)

18 (44%)

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