Table 4 Association between relapse and genomic sequencing (N = 71)
From: Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma
| Relapse or not | ||||
|---|---|---|---|---|
| Characteristics | All (N = 71) | No relapse (N = 30) | Relapse (N = 41) | Fisher’s exact test p value |
| UV | ||||
| Negative | 47 (66%) | 20 (67%) | 27 (66%) | > 0.99 |
| Positive | 24 (34%) | 10 (33%) | 14 (34%) | |
| pRB status | ||||
| Mutate | 32 (45%) | 13 (43%) | 19 (46%) | 0.81 |
| Wild type | 39 (55%) | 17 (57%) | 22 (54%) | |
| p53 status | ||||
| Mutate | 31 (44%) | 13 (43%) | 18 (44%) | > 0.99 |
| Wild type | 40 (56%) | 17 (57%) | 23 (56%) | |
| Virus positive or negative | ||||
| VN | 25 (35%) | 10 (33%) | 15 (37%) | 0.81 |
| VP | 46 (65%) | 20 (67%) | 26 (63%) | |
| pRB and p53 | ||||
| pRB = M, p53 = M | 24 (34%) | 10 (33%) | 14 (34%) | > 0.99 |
| pRB = M, p53 = W | 8 (11%) | 3 (10%) | 5 (12%) | |
| pRB=W, p53 = M | 7 (10%) | 3 (10%) | 4 (10%) | |
| pRB=W, p53 = W | 32 (45%) | 14 (47%) | 18 (44%) | |
