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Fig. 4 | Genome Medicine

Fig. 4

From: Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor

Fig. 4

Cancer chromosome fraction for MAD genes in the GENIE PANET samples. Estimations of the theoretical tumor allelic fraction for MEN1 (red diamond), DAXX/ATRX (red square), and other gene-level mutations (gray circles) for the copy-number model (number of ALT alleles/ploidy) that best represents the pathologist-estimated purities across the different cohorts. A fraction of 1.0 indicates a homozygous variant, and 0.5 a heterozygous variant. Any deviations from these values represent variance in the observed allelic fractions

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