Fig. 3

Scatter plots comparing change in DNA methylation by age (regression coefficient of age) of significant CpGs (FDR < 0.05) between male and female samples for sex-specific (plus symbol for male and cross symbol for female) and unspecific (large star symbol) CpGs on the X-chromosome (a, c) and chromosome 20 (b, d) in LSADT (a, b) and MADT (c, d) cohorts. The colours of CpGs show methylation patterns as in Fig. 1