Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

Table 4 Age-related CpGs by different methylation patterns

Age association	Pattern A	Pattern B	Pattern C	Pattern D	Rest	χ²	p value
LSADT, female
FDR > 0.05	3890	463	2269	122	1834
FDR ≤ 0.05	397	185	675	27	234
% sig	9.26	28.55	22.93	18.12	11.32	371.62	3.77E−79
MADT, female
FDR > 0.05	4128	455	1960	137	1875
FDR ≤ 0.05	159	193	984	12	193
% sig	3.71	29.78	33.42	8.05	9.33	1361.09	1.89E−293
LSADT, male
FDR > 0.05	4195	632	2505	140	1928
FDR ≤ 0.05	92	16	439	9	140
% sig	2.15	2.47	14.91	6.04	6.77	465.40	2.03E−99
MADT, male
FDR > 0.05	3664	536	2305	126	1698
FDR ≤ 0.05	623	112	639	23	370
% sig	14.53	17.28	21.71	15.44	17.89	62.89	7.17E−13

ISSN: 1756-994X