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Fig. 1 | Genome Medicine

Fig. 1

From: Ancestry-specific predisposing germline variants in cancer

Fig. 1

Cancer predisposing genes identified in each ancestry across 9899 TCGA cases across cancer types in the African ancestry, East Asian, and European ancestries. a Ancestry-specific cancer-gene pairs from TCGA dataset containing cancer predisposing variants as identified by multivariate logistic regression analyses. Each number represents carrier frequencies of predisposing genes within that cancer cohort. Genes with significant associations (Wald test FDR < 0.05) are highlighted with blue boxes. b Significant cancer-predisposing gene associations (FDR < 0.05) identified in the African and East Asian ancestries

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