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Fig. 2 | Genome Medicine

Fig. 2

From: A comparison of epigenetic mitotic-like clocks for cancer risk prediction

Fig. 2

Cross-tissue comparison of mitotic clock rate estimates with experiment-derived stem cell division rates. a Scatterplot of the estimated epiTOC2 stem cell division rate per stem cell per year (y-axis, automatically age-adjusted) versus the corresponding literature based estimate for normal tissues (x-axis) profiled as part of the TCGA, as indicated. R2 and P value from a linear regression are given. For each normal tissue, we provide the number of independent samples, and each datapoint represents the median value over these samples. b As a, but now for epiTOC2 stem cell division rate estimates obtained in normal tissue samples not adjacent to cancer. c, d As a, b but now for the HypoClock and the age-adjusted HypoScore derived from it

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