Fig. 4

Perturbation groups inferred by MC-TIMME2 of the responses of the gut microbiome to FOS and PDX across human participants. a FOS and b PDX. Each numbered column represents a perturbation group inferred by MC-TIMME2. For each perturbation group, the top box shows the representative perturbation magnitude over time for that group, with the period of compound administration outlined in yellow. In the grid below, the species which were present in each are indicated. The colors in the grid specify the proportion of a perturbation group’s total members (with each member comprised of a time-series for a species in a participant) belonging to each species