Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma

Table 1 Characteristics of ASMC donors

	With expression data^a	With methylation data^a	With contractile response data	With all three
Sample size	67	70	65	63
Sex (males/females)	36/31	39/31	35/30	34/29
Ancestry (European American/African American)	50/17	51/19	48/17	47/16
Asthma^b (yes/no)	14/53	16/54	13/52	13/50
Median age at time of death (range) (years)	51 (21–85)	51 (21–85)	53 (21–85)	53 (21–85)
Ever smoker^c (%)	46 (69%)	49 (70%)	47 (72%)	46 (73%)
Median cell passage number (range)	4 (1–5)	4 (1–5)	4 (1–5)	4 (1–5)

^aIncludes only samples with genotype data
^bAsthma was determined based on limited medical records and reports available at the time of death and was not the cause of death of any donor listed
^cSmoking history reported after imputation, see Additional File 1 for details

ISSN: 1756-994X