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Table 2 Results of eQTL and meQTL mapping using Matrix eQTL and coQTL discovery by GWAS. Numbers in parentheses for eQTLs and meQTLs refer to the number of unique genes (genes whose expression levels are associated with the QTL) and meCpGs (CpG sites whose methylation levels are associated with the QTL), respectively

From: Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma

Category

Threshold

Vehicle

IL-13

IL-17A

IL-13+IL-17A

eQTLs

FDR = 5%

2595 (140)

3262 (161)

2524 (133)

2765 (139)

meQTLs

FDR = 5%

10,797 (1718)

9859 (1515)

11,274 (1710)

13,222 (2046)

coQTLs

P < 0.01

9087

8705

9776

9370

  1. Sex, age, imputed smoking, and the first two ancestry PCs were included as covariates