Fig. 4
From: A population-based gene expression signature of molecular clock phase from a single epidermal sample
Conserved circadian transcriptional output between human and mouse skin. a Circadian genes in human epidermis and dermis were grouped into 5 categories: (I) no mouse homolog (gray), (II) low amplitude (rAMP ≤ 0.1) and not cycling (P > 0.05) (blue), (III) high amplitude (rAMP > 0.1) and not cycling (orange), (IV) low amplitude and cycling (P < 0.05) (purple), and (V) high amplitude and cycling (red). b, c Phase comparison of high amplitude cycling genes (group V, n = 39 for epidermis and n = 25 for dermis) reveals strong phase conservation between mice and humans. Overlapped circadian genes in epidermis and dermis are shown in red. The gene phases were adjusted to ARNTL/Arntl phase (set to 0). The red dotted line indicates the phase difference with π/3. Mouse data are from Geyfman et al. [28] (Additional file 1: Table S1)