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Table 1 Descriptive statistics

From: Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals

 

GCKD

KORA F3

KORA F4

n

4771

3099

3040

Sex (F)

1896 (39.7%)

1602 (51.7%)

1576 (51.8%)

Age (years)

53, 63, 70

46, 57, 67

44, 56, 67

Age (F) (years)

51, 63, 69

47, 57, 67

44, 56, 67

Age (M) (years)

55, 64, 70

46, 58, 68

45, 57, 68

Lp(a) (mg/dL)

5.0, 11.6, 33.7

5.0, 11.2, 29.2

5.2, 11.7, 30.2

Lp(a) in LMW carriers (mg/dL)

25.7, 53.2, 77.9

18.3, 49.4, 72.6

23.7, 46.8, 66.5

Lp(a) in HMW carriers (mg/dL)

3.8, 8.6, 17.8

4.0, 8.8, 16.7

4.1, 9.0, 17.3

eGFR (mL/min/1.73 m2)

37.0, 46.0, 57.0

76.1, 89.1, 99.2

77.4, 89.3, 100.1

Total cholesterol (mg/dL)

176.5, 207.1, 239.1

191.0, 216.0, 242.0

188.0, 214.0, 240.0

HDL-C (mg/dL)

39.2, 48.2, 61.1

46.0, 56.0, 69.0

45.0, 54.0, 65.0

LDL-C (mg/dL)

89.2, 113.7, 142.7

105.0, 126.0, 148.0

112.0, 134.0, 158.0

Triglycerides (mg/dL)

117.6, 168.0, 238.7

88.0, 135.0, 200.0

71.5, 104.0, 150.0

Type 2 diabetes mellitus

1713 (35.9%)

248 (8.1%)

241 (7.9%)

rs41272114 allele freq.

0.03

0.02

0.02

  1. Continuous variables normally distributed are provided as mean ± standard deviation. Continuous variables non-normally distributed are provided as 25%, 50%, 75% percentiles. eGFR was estimated using the CKD-Epi equation [30]
  2. LMW low molecular weight apo(a) isoforms, HMW high molecular weight apo(a) isoforms, F females, M males, eGFR estimated glomerular filtration rate, Lp(a) lipoprotein(a), HDLC high-density lipoprotein cholesterol, LDLC low-density lipoprotein cholesterol, n number