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Fig. 1 | Genome Medicine

Fig. 1

From: FOXC1-mediated LINC00301 facilitates tumor progression and triggers an immune-suppressing microenvironment in non-small cell lung cancer by regulating the HIF1α pathway

Fig. 1

LINC00301 is up-regulated in both human NSCLC tumorous tissues and cell lines and is beneficial to NSCLC prognosis. a, b Exploring LINC00301 expression in NSCLC cell lines by assembling the Cancer Cell Line Encyclopedia (CCLE) (www.broadinstitute.org/ccle). c LINC00301 expression in NSCLC cell lines and 16HBE/BEAS-2B cells. d, e LINC00301 expression in NSCLC tumor tissues and adjacent normal lung tissues. g According to LINC00301 expression, 120 NSCLC patients were divided into high (n = 60) and low (n = 60) LINC00301 groups. h Kaplan-Meier survival analysis showed that high expression of LINC00301 was correlated with worse prognosis in NSCLC patients. *p < 0.05, means ± SD was shown. Statistical analysis was performed by Student’s t-test and the log-rank test. i, j Correlation between the LINC00301 RNA level and the survival of NSCLC patients from 2437 lung tumors using Kaplan-Meier plotter datasets (2015 version) (http://kmplot.com/analysis/index.php?p=service&cancer=lung)

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Genome Medicine

ISSN: 1756-994X

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