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Table 1 Cell types and abundancies in PDAC primary tumors and metastatic lesions detected by scRNA-Seq

From: Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions

 

Percentage of total cells detected

Patient ID

Primary/metastasis

CAF

DC

EMT

Endo

ETC

TAM

TIL

P01

Primary

8.6

3.7

73.1

3.2

9.3

0.5

1.2

P02

Primary

2.8

6.3

0.7

0.0

51.7

8.4

30.1

P03

Primary

10.7

0.1

82.0

3.7

1.7

1.6

0.1

P04

Primary

24.6

< 0.1

2.8

< 0.1

72.7

< 0.1

< 0.1

P05

Primary

68.3

1.8

< 0.1

2.3

17.7

8.1

1.8

P06

Primary

33.4

3.8

< 0.1

3.1

55.1

4.2

0.4

P07

Primary

14.1

4.5

< 0.1

1.0

17.6

53.7

9.1

P08

Primary

14.3

3.4

< 0.1

1.2

74.0

6.7

0.4

P09

Primary

27.2

1.8

< 0.1

2.8

37.0

31.1

0.2

P10

Primary

8.7

2.0

< 0.1

< 0.1

85.1

4.1

0.1

MET01

Liver Met

< 0.1

< 0.1

< 0.1

< 0.1

97.6

2.1

0.2

MET02

Liver Met

< 0.1

< 0.1

< 0.1

< 0.1

97.0

2.7

0.3

MET03

Omentum Met

< 0.1

< 0.1

< 0.1

< 0.1

30.4

30.4

39.2

MET04

Liver Met

< 0.1

< 0.1

< 0.1

< 0.1

45.8

36.5

17.7

MET05

Liver Met

< 0.1

< 0.1

< 0.1

< 0.1

95.6

3.2

1.2

MET06

Liver Met

< 0.1

< 0.1

< 0.1

< 0.1

93.4

3.8

2.8

  1. Met metastasis, CAF cancer-associated fibroblast, DC dendritic cell, EMT epithelial to mesenchymal transition tumor cell, Endo endothelial cells, ETC epithelial tumor cell, TAM tumor-associated macrophage, TIL tumor-infiltrating lymphocyte