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Fig. 1 | Genome Medicine

Fig. 1

From: Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs

Fig. 1

ARIC discovery meta-analysis (AA and EA) results. In total, 34 independent genome-wide significant CpGs were identified in ARIC meta-analysis to be associated with mtDNA-CN. Dotted line represents genome-wide significance cutoff (P = 5 × 10− 8). CpGs had to be independent and nominally significant in both cohorts (P < 0.05), as well as meet the meta-analysis significance cutoff (P = 5 × 10− 8) to be considered significant (red dots). Gray and black dots represents CpGs that were not significant based on this criteria

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