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Fig. 6 | Genome Medicine

Fig. 6

From: The murine Microenvironment Cell Population counter method to estimate abundance of tissue-infiltrating immune and stromal cell populations in murine samples using gene expression

Fig. 6

mMCP-counter discriminates between control CK mice and Alzheimer’s disease brain tissues. a Heatmap showing that clustering of samples on mMCP-counter scores accurately separates hippocampus samples from control CK samples and induced Alzheimer’s disease (AD) at different time points (n = 6 AD and n = 6 CK). The heatmap illustrates row Z-scores for all included cell populations. b Detailed differences in mMCP-counter scores between CK and induced AD hippocampus samples. The color code of the individual data points refers to the legend of panel a. Comparisons are computed using Mann-Whitney tests. *p < 0.05, **p < 0.01

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